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CAS No. : 501-97-3
MCE 国际站:Desaminotyrosine
产品活性:Desaminotyrosine 是一种微生物相关的代谢物,通过扩大 I 型干扰素 (type I interferon) 信号来阻止 influenza 的发生。
研究领域:Anti-infection | Metabolic Enzyme/Protease
作用靶点:Influenza Virus | Endogenous Metabolite
结构分类:酚类 | 单酚类 | 酮、醛、酸
In Vivo: Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice.
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货号: HY-W015346
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