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MCE 国际站:Carbonic Anhydrase 4 Protein, Human (His)
Carbonic Anhydrase 4 Protein, Human (His)是一种在 E. coli 表达的,N 末端有 His 标签的重组人 Mouse Carbonic Anhydrase 4。Carbonic Anhydrase 4 (CA4) 蛋白是一种锌金属酶,催化 CO2 和 HCO3- 的可逆水合和脱水。
Synonyms: rHuCarbonic Anhydrase 4, His; Carbonic Anhydrase 4; Carbonate Dehydratase IV; Carbonic Anhydrase IV; CA4
Species: Human
Source: E. coli
Biological Activity: The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
研究背景:The human carbonic anhydrase IV (CA4) gene, located on chromosome 17q22, was the first identified membrane-bound isozyme in the 16-member carbonic anhydrase (CA) gene family and contains 1,170 base pairs. The CA4 enzyme is involved in the formation of gastric acid and participates in acid-base homeostasis. CA4 is expressed in normal human stomach tissues. CA4 may serve an important role in gastric cancer (GC) tumorigenesis by inhibiting cellular proliferation via regulating the expression of cell cycle‑associated proteins. CA4 may serve as a diagnostic biomarker and a potential therapeutic target in GC.
蛋白编号:P22748 (A19-K283)
基因 ID:762
产品分类:酶和调节子 | 碳酸酐酶 | 碳酸酐酶 4 | 酶和调节子 | 裂解酶
Categories:Enzymes & Regulators | Carbonic Anhydrase | Carbonic Anhydrase 4 (CA IV) | Enzymes & Regulators | Lyases (EC 4)
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