耗材描述
Carvacrol
产品活性:Carvacrol 是一种具有口服活性的单萜酚,可以从大量芳香植物中提取,包括百里香和牛至,具有抗氧化、抗菌、抗真菌、抗癌、抗炎、保肝、解痉和血管松弛剂特性。Carvacrol 还引起 G0/G1 细胞周期阻滞,下调 Notch-1 和 Jagged-1,诱导细胞凋亡 (Apoptosis)。Carvacrol 被用作低浓度的食品调味成分和防腐剂,以及化妆品配方中的香味成分。
产品来源: https://www.medchemexpress.cn/carvacrol.html
研究领域:Neuronal Signaling | Stem Cell/Wnt | Apoptosis | Anti-infection | Metabolic Enzyme/Protease
作用靶点:Notch | Apoptosis | Fungal | Endogenous Metabolite | Bacterial
来源:植物 | 唇形科
结构分类:酚类 | 单酚类 | 结构分类
In Vivo: Carvacrol (50 or 100 mg/kg; i.p.) inhibits the mechanical hyper-nociception induced by carrageenan in mice.
Carvacrol (20, 40, and 80 mg/kg, intragastric gavage, during six days before LPS injection) reduces inflammation (reduces serum proinflammatory molecules) in rats.
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