Panaxadiol 产品活性：Panaxadiol (20(R)-Panaxadiol) 是一种具有口服活性的 HIF-1α/STAT3 抑制剂。Panaxadiol 可以抑制 HIF-1α 和 STAT3，然后导致 programmed cell death-ligand 1 (PD-L1) 表达的下调。Panaxadiol 具有抗癌、保护心脏、抗心律失常和抗氧化的活性。 产品来源： https://www.medchemexpress.cn/Panaxadiol.html 研究领域：Immunology/Inflammation | Metabolic Enzyme/Protease | JAK/STAT Signaling | Stem Cell/Wnt 作用靶点：PD-1/PD-L1 | HIF/HIF Prolyl-Hydroxylase | STAT 来源：植物 | 五加科 | 人参 结构分类：萜类 | 三萜 | 结构分类 In Vitro: Panaxadiol (1-10 μM, 12 h) inhibits PD-L1 expression in human colon cancer cells. Panaxadiol (1-10 μM, 12 h) inhibits the expression of PD-L1 by suppressing HIF-1α and STAT3 in HCT116 cells. In Vivo: Panaxadiol (oral gavage; 10 or 30 mg/kg; once every 3 days; 30 d) inhibits the growth of HCT116 cells in a xenograft model. 相关产品：Covalent Screening Library Plus | Natural Product Library Plus | Bioactive Compound Library Plus | Epigenetics Compound Library | Immunology/Inflammation Compound Library | JAK/STAT Compound Library | Kinase Inhibitor Library | Metabolism/Protease Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Small Molecule Immuno-Oncology Compound Library | Anti-Aging Compound Library | Covalent Screening Library | Differentiation Inducing Compound Library | Reprogramming Compound Library | Lipid Compound Library | Oxygen Sensing Compound Library | Medicine Food Homology Compound Library | Terpenoids Library | Orally Active Compound Library | Glutamine Metabolism Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Breast Cancer Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Obesity Compound Library | Angiogenesis-Related Compound Library | Transcription Factor-Targeted Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Natural Product Library | Protein-protein Interaction Inhibitor Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Anti-Prostate Cancer Compound Library | Cancer Stem Cells Compound Library | Heterocyclic Compound Library | Metabolic Enzyme Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Anti-Hematopathy Compound Library | Anti-Ovarian Cancer Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Anti-Gastric Cancer Compound Library | Anti-Fibrosis Compound Library | Deferoxamine mesylate | Stattic | DMOG | Fludarabine | PX-478 | Roxadustat | Minocycline hydrochloride | Atezolizumab | AG490 | Pembrolizumab | LW6 | Belzutifan | Cilengitide | Homoharringtonine | Chloramphenicol | Niclosamide | Nivolumab | AS1517499 | BMS-1 | C188-9 | Artesunate | PT-2385 | BMS-202 | TPCA-1 | Chlorogenic acid | Anti-Mouse PD-1 Antibody (RMP1-14) | Colivelin TFA | Napabucasin | JQ-1 (carboxylic acid) | Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2) 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。