耗材描述
Apigenin 7-glucoside
产品活性:Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside),ROS 清除剂,具有抗增殖,抗氧化活性。
产品来源: https://www.medchemexpress.cn/Apigenin-7-glucoside.html
研究领域:Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease
作用靶点:Reactive Oxygen Species
来源:植物 | 豆科 | 白花草木犀 | 植物 | 菊科
结构分类:黄酮类 | 黄酮 | 酚类 | 多酚类
In Vitro: Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.
Apigenin 7-glucoside specifically induces the differentiation of CD34+ cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.
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