Deltamethrin 产品活性：Deltamethrin (Decamethrin) 是一种具有口服活性的人工合成的拟除虫菊酯类杀虫剂。Deltamethrin通过抑制 Nrf2/HO-1 通路诱导氧化应激，导致炎症反应和细胞凋亡 (apoptosis)，通过诱导细胞凋亡 (apoptosis) 而发挥抗肿瘤作用，可广泛用于害虫防治。 产品来源： https://www.medchemexpress.cn/deltamethrin.html 研究领域：Metabolic Enzyme/Protease | Neuronal Signaling | Membrane Transporter/Ion Channel | Apoptosis | NF-κB | Immunology/Inflammation 作用靶点：Endogenous Metabolite | Calcium Channel | Caspase | Apoptosis | Bcl-2 Family | NF-κB | Interleukin Related 结构分类：其他类 | 结构分类 In Vitro: Deltamethrin (5-60 μM, 24 h) increases cytosolic free Ca2+ concentration and induces apoptosis in a concentration-dependent manner in OC2 human oral cancer cells. Deltamethrin (0.5-100 μM, 24 h) inhibits thymocytes viability. Deltamethrin (10-50 μM, 1-6 h) shows a concentration- and time-dependent enhancement in caspase-3 activity in murine thymocytes. Deltamethrin (10-50 μM, 18 h) induces apoptosis in thymocytes. In Vivo: Deltamethrin (5.6-18 mg/kg, Oral, once a day for 15 days) induces oxidative stress in mice. Deltamethrin (60 mg/kg, Intraperitoneal injection, single dose) can increase the activity of Choline acetyltransferase (ChAT) in the striatum in rats. Deltamethrin (15-45 mg/kg, Gavage, once a day for 12 weeks) promotes cardiomyocyte inflammation and apoptosis through inhibiting the Nrf2/HO-1 signaling pathway in quails. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Immunology/Inflammation Compound Library | Membrane Transporter/Ion Channel Compound Library | Metabolism/Protease Compound Library | Neuronal Signaling Compound Library | NF-κB Signaling Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Oxygen Sensing Compound Library | Pyroptosis Compound Library | Orally Active Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Angiogenesis-Related Compound Library | Mitochondria-Targeted Compound Library | Transcription Factor-Targeted Library | Anti-Cancer Natural Product Library | Human Metabolite Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Mitochondrial Toxicity Compound Library | Cell Death Library | Ion Channel Compound Library | Multi-Target Compound Library | Radioprotector Library | Mitophagy Compound Library | Bioactive Compound Library Max | Pesticide Compound Library | MG-132 | Rapamycin | Phorbol 12-myristate 13-acetate | 3-Methyladenine | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | Venetoclax | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | ATP | Retinoic acid | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。