Pentoxifylline 产品活性：Pentoxifylline (BL-191) 是一种血液流变学改善剂。Pentoxifylline 是一种具有口服活性的，非选择性的磷酸二酯酶 (PDE) 抑制剂，具有免疫调节、抗炎、血液流变学改善、抗纤溶和抗增殖作用。Pentoxifylline 可用于研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。 产品来源： https://www.medchemexpress.cn/Pentoxifylline.html 研究领域：Metabolic Enzyme/Protease | Autophagy | Anti-infection 作用靶点：Phosphodiesterase (PDE) | Autophagy | HIV In Vitro: Pentoxifylline (0.1-50 mM; 24-48 hours) inhibits cell proliferation in a dose-dependent manner. Pentoxifylline (0.5 mM; 12-36 hours) increases apoptosis and decreases autophagy levels in MDA-MB-231 cells. Pentoxifylline (0.5 mM; 12-36 hours) induces autophagy in MDA-MB-231 cells. Pentoxifylline (0.5 mM; 24-48 hours) blocks cell cycle at the G0/G1 phase. Pentoxifylline results in high LC3-II/LC3-ratio. In Vivo: Pentoxifylline (200 mg/kg; i.p.) has a protective effect on rats with transient global ischemia and reduces cognitive impairment. 相关产品：Natural Product-like Compound Library | Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Anti-Infection Compound Library | Metabolism/Protease Compound Library | FDA-Approved Drug Library | Anti-Cancer Compound Library | Antiviral Compound Library | Autophagy Compound Library | Drug Repurposing Compound Library | Anti-Cardiovascular Disease Compound Library | Anti-COVID-19 Compound Library | NMPA-Approved Drug Library | Orally Active Compound Library | FDA Approved & Pharmacopeial Drug Library | Anti-Alzheimer's Disease Compound Library | Drug-Induced Liver Injury (DILI) Compound Library | Neurodegenerative Disease-related Compound Library | Rare Diseases Drug Library | Anti-Colorectal Cancer Compound Library | Children’s Drug Library | FDA-Approved Anticancer Drug Library | Human Metabolite Library | Anti-Prostate Cancer Compound Library | Non-steroidal Anti-Inflammatory Compound Library | Coagulation and Anti-coagulation Compound Library | Off-patent Drug Library | Metabolic Enzyme Compound Library | Highly Selective Inhibitors Library | Highly Selective Activators Library | Cell Death Library | Multi-Target Compound Library | Radiosensitizer Library | Bioactive Compound Library Max | Chloroquine | Doxorubicin hydrochloride | 5-Fluorouracil | IBMX | Q-VD-OPh | Bucladesine sodium | Valproic acid | Panobinostat | Shikonin | Probenecid | Kaempferol | Dimethyl fumarate | Hydroxyurea | Plerixafor | Maraviroc | Birinapant | Baicalin | Flavopiridol | Ritonavir | Ivermectin | Fasudil Hydrochloride | Ebselen | Rolipram | Roflumilast | Lysozyme from chicken egg white | CK-666 | Betulinic acid 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。