Episilvestrol 产品活性：Episilvestrol 是 silvestrol 的衍生物，从 Aglaia perviridis 中分到，能够抑制 eIF4A 靶作用的转录过程。 产品来源： https://www.medchemexpress.cn/Episilvestrol.html 研究领域：Cell Cycle/DNA Damage | Autophagy 作用靶点：Eukaryotic Initiation Factor (eIF) | Autophagy 来源：植物 | 楝科 | 碧绿米仔兰 结构分类：其他类 In Vitro: Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is cytotoxic activity against several human cancer cell lines, such as Lu1, LNCaP, MCF-7 and HUVEC cells, with ED50s of 3.8, 3.8, 5.5 and 15.3 nM, respectively. The GI50s of Episilvestrol against the cell proliferation of NCI-H460 and MCF-7 cels are 17.96 nM and 17.96 nM after first test and 15.6 nM and 18.7 nM after 2 months via SRB assay. Episilvestrol also suppresses HK1 cells and EBV-positive C666.1 NPC cells. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | GCN2iB | Rocaglamide | GCN2-IN-1 | Zotatifin | 4EGI-1 | ATPγS tetralithium salt | Silvestrol | 2BAct | CR-1-31-B | ISRIB | GCN2-IN-6 | 4E1RCat | eIF4A3-IN-2 | eIF4A3-IN-1 | SBI-0640756 | 4E2RCat | Briciclib | EIF2α activator 1 | ML291 | Rohinitib | EIF2α activator 2 | eIF4A3-IN-8 | eIF4A3-IN-16 | eIF4E-IN-3 | CMLD012612 | eIF4A3-IN-10 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。