Product Introduction
Bioactivity


英文名: M2N12

描述: M2N12 是一种高度选择性的细胞分裂周期蛋白磷酸酶 25C 抑制剂，IC50值为 0.09 μM。它还抑制 Cdc25A 和 Cdc25B 的活性，IC50值分别为 0.53 μM 和 1.39 μM。它具有抗肿瘤活性，可研究癌症。

体外活性: M2N12 对五种肿瘤细胞系及一种正常细胞系表现出细胞毒性活性，涉及的细胞系包括A-549（IC50 = 3.92 μM）、MDA-MB-231（IC50 = 4.63 μM）、KB（IC50 = 5.05 μM）、KB-VIN（IC50 = 6.81 μM）、MCF-7（IC50 = 4.71 μM）和HBE（IC50 = 6.00 μM）[1]。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 8 mg/mL (20.31 mM)


关键字: CDK | M-2N12 | HBE | KB-VIN | A-549 | M2N12 | Cyclin dependent kinase | MCF-7 | cancer | Inhibitor | inhibit

相关产品: PTP1B-IN-2 | PP5-IN-1 | Stevisaliosides D | Trimyristin | DT-061 | Boehmenan | LYP-IN-4 | Tartaric acid disodium dihydrate | Sodium etidronate | BCI-215

相关库: Glycometabolism Compound Library | Cell Cycle Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Phosphatase Inhibitor Library | Inhibitor Library | Anti-Cancer Active Compound Library | Highly Selective Inhibitor Library | Metabolism Compound Library | Bioactive Compound Library