化合物P11 acetate TP1879L1
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Product IntroductionBioactivity英文名: P11 acetate描述: P11 acetate 是一种整合素 αvβ3-玻连蛋白相互作用拮抗剂 (IC50 = 2.74 nM)。体外活性: P11 acetate
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Product Introduction
Bioactivity
英文名: P11 acetate
描述: P11 acetate 是一种整合素 αvβ3-玻连蛋白相互作用拮抗剂 (IC50 = 2.74 nM)。
体外活性: P11 acetate 对avb3-GRGDSP相互作用表现出强烈的拮抗作用(IC50 = 25.72 nM)[1]。通过激活caspases并与p53表达增加有关的机制，P11 acetate抑制了HUVEC细胞的增殖并诱导HUVEC细胞死亡[2]。与PBS对照组相比，P11 acetate显著抑制了bFGF诱导的细胞迁移[3]。
存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: P11 acetate | P11 Acetate | P 11 Acetate | P-11 Acetate
相关产品: Valategrast hydrochloride | Synstatin (92-119) | Gantofiban | Orbofiban TFA | Arg-Gly-Asp TFA (99896-85-2(free base)) | OSU-T315 | Bimosiamose | BIRT-377 | Cyclo(RADfK) | Egaptivon pegol
相关库: Bioactive Compounds Library Max | Inhibitor Library | Peptide Compound Library | Cytoskeletal Signaling Pathway Compound Library | PPI Inhibitor Library | Preclinical Compound Library | Bioactive Compound Library
Bioactivity
英文名: P11 acetate
描述: P11 acetate 是一种整合素 αvβ3-玻连蛋白相互作用拮抗剂 (IC50 = 2.74 nM)。
体外活性: P11 acetate 对avb3-GRGDSP相互作用表现出强烈的拮抗作用(IC50 = 25.72 nM)[1]。通过激活caspases并与p53表达增加有关的机制，P11 acetate抑制了HUVEC细胞的增殖并诱导HUVEC细胞死亡[2]。与PBS对照组相比，P11 acetate显著抑制了bFGF诱导的细胞迁移[3]。
存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: P11 acetate | P11 Acetate | P 11 Acetate | P-11 Acetate
相关产品: Valategrast hydrochloride | Synstatin (92-119) | Gantofiban | Orbofiban TFA | Arg-Gly-Asp TFA (99896-85-2(free base)) | OSU-T315 | Bimosiamose | BIRT-377 | Cyclo(RADfK) | Egaptivon pegol
相关库: Bioactive Compounds Library Max | Inhibitor Library | Peptide Compound Library | Cytoskeletal Signaling Pathway Compound Library | PPI Inhibitor Library | Preclinical Compound Library | Bioactive Compound Library
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