VU 0469650 T29118
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Product IntroductionBioactivity英文名: VU 0469650描述: VU 0469650 是一种强效、选择性的 mGluR1 负异位调节剂（IC50 = 99 nM）。体内活性: VU 0469650 (10
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Product Introduction
Bioactivity
英文名: VU 0469650
描述: VU 0469650 是一种强效、选择性的 mGluR1 负异位调节剂（IC50 = 99 nM）。
体内活性: VU 0469650 (10 mg/kg; I.P.; once; male Sprague-Dawley rats) shows an excellent selectivity profile and good exposure in both plasma and brain samples.[1] VU 0469650 (0.2 mg/kg; I.V.; once; male Sprague-Dawley rats) exhibits moderate to high clearance, a moderate volume of distribution, and a half-life of approximately 1 hour.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 45.0 mg/mL (112.2 mM)
DMSO : 90.0 mg/mL (224.5 mM)
相关产品: AZD 9272 | Aniracetam | MNI 137 | LY392098 | CDPPB | ABP688 | VU6005649 | TAT-GluA2 3Y acetate(1404188-93-7 free base) | Kynurenic acid | IDRA-21
相关库: Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Bioactive Compound Library
Bioactivity
英文名: VU 0469650
描述: VU 0469650 是一种强效、选择性的 mGluR1 负异位调节剂（IC50 = 99 nM）。
体内活性: VU 0469650 (10 mg/kg; I.P.; once; male Sprague-Dawley rats) shows an excellent selectivity profile and good exposure in both plasma and brain samples.[1] VU 0469650 (0.2 mg/kg; I.V.; once; male Sprague-Dawley rats) exhibits moderate to high clearance, a moderate volume of distribution, and a half-life of approximately 1 hour.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 45.0 mg/mL (112.2 mM)
DMSO : 90.0 mg/mL (224.5 mM)
相关产品: AZD 9272 | Aniracetam | MNI 137 | LY392098 | CDPPB | ABP688 | VU6005649 | TAT-GluA2 3Y acetate(1404188-93-7 free base) | Kynurenic acid | IDRA-21
相关库: Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Bioactive Compound Library
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