Product Introduction
Bioactivity


英文名: Rp-8-bromo-Cyclic AMPS (sodium salt)

描述: Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 30 mg/mL
DMSO : 25 mg/mL
PBS (pH 7.2) : 10 mg/mL
Ethanol : 0.5 mg/mL


关键字: Rp 8 bromo Cyclic AMPS (sodium salt) | Rp-8-bromo-Cyclic AMPS | Rp8bromoCyclic AMPS (sodium salt)