Rp-8-bromo-Cyclic AMPS (sodium salt) T36677

Product Introduction
Bioactivity


英文名: Rp-8-bromo-Cyclic AMPS (sodium salt)

描述: Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 30 mg/mL
DMSO : 25 mg/mL
PBS (pH 7.2) : 10 mg/mL
Ethanol : 0.5 mg/mL


关键字: Rp 8 bromo Cyclic AMPS (sodium salt) | Rp-8-bromo-Cyclic AMPS | Rp8bromoCyclic AMPS (sodium salt)

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途