Product Introduction
Bioactivity


英文名: Indinavir sulfate

描述: Indinavir sulfate (L735524 sulfate) 是一种 HIV 蛋白酶抑制剂。它抑制 HIV-1 蛋白酶，IC50 值为 0.41 nM，Ki 值为 0.24 nM。它也是SARS-CoV 3CLpro 抑制剂，IC50为 1.71 μM。

体外活性: At low concentrations (0.0003-10?μmol/l) indinavir acts as a positive allosteric modulator (EC50?=?0.021?μmol/l), whereas at concentrations greater than 10?μmol/l (30-100?μmol/l) indinavir acts as an inhibitor of the α7-nicotinic acetylcholine receptor.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (140.48 mM)


关键字: Inhibitor | MK639 | L-735524 Sulfate | L 735524 | Huh7 | Matrix metalloproteinases | L-735524 | PBMC | MK 639 | Indinavir sulfate | MMP | MK-639 | Indinavir Sulfate | SARS coronavirus | HIV Protease | Apoptosis | hepatocarcinomas | L735524 | L735524 Sulfate | Human immunodeficiency virus | MK-639 Sulfate | Indinavir | inhibit | CD4 T cells | MK639 Sulfate | MK 639 Sulfate | HIV | L 735524 Sulfate | SARS-CoV

相关产品: Kansuinine B | Nafamostat mesylate | SARS-CoV-2 nsp14-IN-3 | Glecaprevir | SARS-CoV-2-IN-66 | SARS-CoV-2-IN-63 | Zevotrelvir | SARS-CoV-2-IN-53 | Azelastine | 4'-O-Methylbavachalcone

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | FDA-Approved & Pharmacopeia Drug Library | Anti-Cancer Drug Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | EMA Approved Drug Library | Anti-Viral Compound Library | Bioactive Compound Library