硫酸茚地那韦 T5863

Product Introduction
Bioactivity


英文名: Indinavir sulfate

描述: Indinavir sulfate (L735524 sulfate) 是一种 HIV 蛋白酶抑制剂。它抑制 HIV-1 蛋白酶，IC50 值为 0.41 nM，Ki 值为 0.24 nM。它也是SARS-CoV 3CLpro 抑制剂，IC50为 1.71 μM。

体外活性: At low concentrations (0.0003-10?μmol/l) indinavir acts as a positive allosteric modulator (EC50?=?0.021?μmol/l), whereas at concentrations greater than 10?μmol/l (30-100?μmol/l) indinavir acts as an inhibitor of the α7-nicotinic acetylcholine receptor.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (140.48 mM)


关键字: Inhibitor | MK639 | L-735524 Sulfate | L 735524 | Huh7 | Matrix metalloproteinases | L-735524 | PBMC | MK 639 | Indinavir sulfate | MMP | MK-639 | Indinavir Sulfate | SARS coronavirus | HIV Protease | Apoptosis | hepatocarcinomas | L735524 | L735524 Sulfate | Human immunodeficiency virus | MK-639 Sulfate | Indinavir | inhibit | CD4 T cells | MK639 Sulfate | MK 639 Sulfate | HIV | L 735524 Sulfate | SARS-CoV

相关产品: Kansuinine B | Nafamostat mesylate | SARS-CoV-2 nsp14-IN-3 | Glecaprevir | SARS-CoV-2-IN-66 | SARS-CoV-2-IN-63 | Zevotrelvir | SARS-CoV-2-IN-53 | Azelastine | 4'-O-Methylbavachalcone

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | FDA-Approved & Pharmacopeia Drug Library | Anti-Cancer Drug Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | EMA Approved Drug Library | Anti-Viral Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途