化合物Zd-2138 T68173
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Product IntroductionBioactivity英文名: ZD-2138描述: ZD-2138是一种有效且具有选择性的5-脂氧合酶（5-LOX）的特异性抑制剂，抑制了过敏原诱导的肺支气管收缩，可减少豚鼠孤立气道的神经诱发性快速激
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Product Introduction
Bioactivity
英文名: ZD-2138
描述: ZD-2138是一种有效且具有选择性的5-脂氧合酶（5-LOX）的特异性抑制剂，抑制了过敏原诱导的肺支气管收缩，可减少豚鼠孤立气道的神经诱发性快速激肽能收缩。ZD-2138可用来治疗哮喘疾病。
体外活性: The 5-lipoxygenase inhibitor ZD-2138 (1 μM) significantly inhibited these neurally mediated tachykinergic contractions, by approximately 50%, yet had no effect on the contractions evoked by stimulating tachykinergic fibers in an action potential-independent fashion with capsaicin or by exogenously applied neurokinin A.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 15 mg/mL (37.74 mM)
关键字: Ici-D-2138 | Ici-D 2138 | ZD2138 | ZD-2138 | ZD 2138
相关产品: Meclofenoxate hydrochloride | 3'-Demethylnobiletin | RWJ 63556 | CBS-1114 HCl | Caffeic Acid | Efletirizine | COX-2/15-LOX-IN-4 | Trichosanatine | ML351 | Cirsiliol
相关库: Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library
Bioactivity
英文名: ZD-2138
描述: ZD-2138是一种有效且具有选择性的5-脂氧合酶（5-LOX）的特异性抑制剂，抑制了过敏原诱导的肺支气管收缩，可减少豚鼠孤立气道的神经诱发性快速激肽能收缩。ZD-2138可用来治疗哮喘疾病。
体外活性: The 5-lipoxygenase inhibitor ZD-2138 (1 μM) significantly inhibited these neurally mediated tachykinergic contractions, by approximately 50%, yet had no effect on the contractions evoked by stimulating tachykinergic fibers in an action potential-independent fashion with capsaicin or by exogenously applied neurokinin A.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 15 mg/mL (37.74 mM)
关键字: Ici-D-2138 | Ici-D 2138 | ZD2138 | ZD-2138 | ZD 2138
相关产品: Meclofenoxate hydrochloride | 3'-Demethylnobiletin | RWJ 63556 | CBS-1114 HCl | Caffeic Acid | Efletirizine | COX-2/15-LOX-IN-4 | Trichosanatine | ML351 | Cirsiliol
相关库: Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library
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