化合物Zd-2138 T68173

Product Introduction
Bioactivity


英文名: ZD-2138

描述: ZD-2138是一种有效且具有选择性的5-脂氧合酶（5-LOX）的特异性抑制剂，抑制了过敏原诱导的肺支气管收缩，可减少豚鼠孤立气道的神经诱发性快速激肽能收缩。ZD-2138可用来治疗哮喘疾病。

体外活性: The 5-lipoxygenase inhibitor ZD-2138 (1 μM) significantly inhibited these neurally mediated tachykinergic contractions, by approximately 50%, yet had no effect on the contractions evoked by stimulating tachykinergic fibers in an action potential-independent fashion with capsaicin or by exogenously applied neurokinin A.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 15 mg/mL (37.74 mM)


关键字: Ici-D-2138 | Ici-D 2138 | ZD2138 | ZD-2138 | ZD 2138

相关产品: Meclofenoxate hydrochloride | 3'-Demethylnobiletin | RWJ 63556 | CBS-1114 HCl | Caffeic Acid | Efletirizine | COX-2/15-LOX-IN-4 | Trichosanatine | ML351 | Cirsiliol

相关库: Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途