Product IntroductionBioactivity英文名:
5,7,4'-Trimethoxyflavone描述: 5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) 是从泰国著名的药用植物 Kaempferia parviflora 中分离出来的一种天然产物。它以浓度依赖性方式显著有效抑制 SNU-16 人胃癌细胞的增殖,诱导细胞凋亡。
体外活性: 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of PARP protein. 5,7,4'-Trimethoxyflavone is significantly effective at inhibiting the proliferation of SNU-16 human gastric cancer cells in a concentration-dependent manner.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 22.5 mg/mL (72.04 mM)
关键字:
Apoptosis |
poly ADP ribose polymerase |
5,7,4' Trimethoxyflavone |
Caspase |
inhibit |
5,7,4'Trimethoxyflavone |
5,?7,?4'-?Trimethoxyflavone |
Inhibitor |
PARP |
Endogenous Metabolite |
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Rotenone |
Linderalactone |
Escin相关库:
Anti-Neurodegenerative Disease Compound Library |
Anti-Prostate Cancer Compound Library |
Tobacco Monomer Library |
Selected Plant-Sourced Compound Library |
Chinese Pharmacopoeia Natural Product Library |
Bioactive Compounds Library Max |
Epigenetics Compound Library |
Traditional Chinese Medicine Monomer Library |
Flavonoid Natural Product Library |
RO5 Drug-like Natural Product Library