AMIGO2, Mouse, 重组蛋白 (His) TMPK-01072
面议
- TargetMol
- 生产商
- 进口
- 美国
- 现货
- 全国
- 3
- 0
Product IntroductionBioactivity英文名: AMIGO2 Protein, Mouse, Recombinant (His)描述: Bromodomain and extraterminal domain inhi
AI问答
配套的仪器设备？
可以搭配的相关耗材试剂？
耗材描述
Product Introduction
Bioactivity
英文名: AMIGO2 Protein, Mouse, Recombinant (His)
描述: Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: AMIGO 2 | ALI-1 | ALI 1
Bioactivity
英文名: AMIGO2 Protein, Mouse, Recombinant (His)
描述: Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: AMIGO 2 | ALI-1 | ALI 1
猜你喜欢
感兴趣产品