AMIGO2, Mouse, 重组蛋白 (His) TMPK-01072
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | TMPK-01072 | ¥17,800.00 | 询底价 |
100 μg | TMPK-01072 | ¥2,660.00 | 询底价 |
500 μg | TMPK-01072 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AMIGO2 Protein, Mouse, Recombinant (His)
描述: Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: AMIGO 2 | ALI-1 | ALI 1
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途