Product Introduction
Bioactivity


英文名: Chrysosplenol D

描述: Chrysosplenol D 属于甲氧基黄酮类化合物，可诱导 ERK1/2 介导的三阴性人乳腺癌细胞凋亡。它还显示出抗炎和中等抗锥虫活性。

体外活性: Trace amounts of the antimalarial sesquiterpene lactone artemisinin may account for the activity of the n-hexane fraction but only the methoxylated flavonoids artemetin, chrysoplenetin, chrysosplenol-D and cirsilineol can account for the activity of the chloroform extract. These purified flavonoids were found to have IC50 values at 2.4 - 6.5 x 10(-5)M against P. falciparum in vitro compared with an IC50 value of about 3 x 10(-8)M for purified artimisinin[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (152.65 mM)


关键字: cancer | Apoptosis | inhibit | ERK1/2 | Inhibitor | antitrypanosomal | breast | anti-inflammatory | Chrysosplenol D

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相关库: Anti-Inflammatory Traditional Chinese Medicine Compound Library | NF-κB Signaling Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Active Compound Library | Anti-Parasitic Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Pancreatic Cancer Compound Library | Antiparasitic Natural Product Library