猫眼草酚D TN1493

Product Introduction
Bioactivity


英文名: Chrysosplenol D

描述: Chrysosplenol D 属于甲氧基黄酮类化合物，可诱导 ERK1/2 介导的三阴性人乳腺癌细胞凋亡。它还显示出抗炎和中等抗锥虫活性。

体外活性: Trace amounts of the antimalarial sesquiterpene lactone artemisinin may account for the activity of the n-hexane fraction but only the methoxylated flavonoids artemetin, chrysoplenetin, chrysosplenol-D and cirsilineol can account for the activity of the chloroform extract. These purified flavonoids were found to have IC50 values at 2.4 - 6.5 x 10(-5)M against P. falciparum in vitro compared with an IC50 value of about 3 x 10(-8)M for purified artimisinin[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (152.65 mM)


关键字: cancer | Apoptosis | inhibit | ERK1/2 | Inhibitor | antitrypanosomal | breast | anti-inflammatory | Chrysosplenol D

相关产品: Luteolin-4'-O-glucoside | Kazinol U | NO-prednisolone | Ayanin | Cucurbitacin D | 6,4'-Dihydroxy-7-methoxyflavanone | Apilimod | Secukinumab | Jolkinolide B | Nudiposide

相关库: Anti-Inflammatory Traditional Chinese Medicine Compound Library | NF-κB Signaling Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Active Compound Library | Anti-Parasitic Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Pancreatic Cancer Compound Library | Antiparasitic Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途