L129223-5gLoratadine
面议
- 阿拉丁
- 生产商
- L129223-5g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C22H23ClN2O2
- 分子量382.88
- Beilstein号
- EC号 MFCD00672869
- MDL号 MFCD00672869
- PubChem编号 24278525
属性
熔点 | 137°C |
溶解性 | Soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), chloroform, and methanol. |
存贮条件 | 储存温度 2-8°C |
描述
应用 | A peripheral histamine H1 receptor agonist. |
产品介绍 | Loratadine是一种选择性的,逆向外周组胺H1受体激动剂,IC50大于32 μM。 |
备注 | Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. |
生化机理 | Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist (IC50 > 32 μM). |
别名 | 克敏能;氯雷他定;4-(8-氯-5,6-二氢-11H-苯并[5,6]环庚基[1,2-b]并吡啶-11-烯)-1-哌啶羧酸乙脂;4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester;Loratidine;SCH 29851; SCH29851; SCH-29851 |
Reaxys-RN | 4273483 |
个人防护设备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
RTECS | TM6129200 |
WGK德国 | 2 |
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