A127102-5mgAN-2728
面议
- 阿拉丁
- 生产商
- A127102-5mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C14H10BNO3
- 分子量251.05
- Beilstein号
- EC号 MFCD17169940
- MDL号
- PubChem编号
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
生化机理 |
AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines. AN-2728 appears to have good therapeutic potential, although further and larger trials are required to assess the long-term safety and characterize the broad utility of this drug. AN-2728 shows potent activity both in vitro and in vivo. AN-2728 is now in clinical development for the topical treatment of psoriasis and being pursued for the topical treatment of atopic dermatitis. |
别名 | AN2728;AN 2728;4-((1,3-二氢-1-羟基-2,1-苯并氧杂硼杂环戊烷-5-基)氧基)苯甲腈;;AN2728;AN 2728; 4-((1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy)benzonitrile |
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