T129355-25gTolnaftate
面议
- 阿拉丁
- 生产商
- T129355-25g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C19H17NOS
- 分子量307.41
- EC号 219-266-6
- MDL号 MFCD00056611
- PubChem编号 24900394
属性
熔点 | 110-113°C |
敏感性 | 对热敏感 |
溶解性 | DMSO 62 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度 2-8°C |
描述
应用 | It is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete′s foot, jock itch, and ringworm. It also has been used as a comparator compound for antifungal efficiency studies. |
产品介绍 | Tolnaftate 是一种合成的硫代氨基甲酸酯,用作抗真菌剂。 |
备注 | Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. |
生化机理 | It prevents ergosterol biosynthesis by inhibiting squalene epoxidase. It has also been reported to distort the hyphae and to stunt mycelial growth in susceptible organisms. Tolnaftate inhibits biosynthesis of aflatoxin. |
别名 | 托萘酯; 甲基(3-甲苯基)硫代氨基甲酸 O-2-萘酯;Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester;O-2-Naphthyl Methyl(3-methylphenyl)carbamothioate;Aftate; Tinactin |
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