耗材描述
- 分子式 C26H29N3O6·HCl
- 分子量515.99
- EC号 259-198-4
- MDL号 MFCD00057327
- PubChem编号 24277856
属性
敏感性 | 对光敏感 |
溶解性 | Soluble in DMSO (1 mg/ml), water (slightly), methanol (50 mg/ml), chloroform (slightly), and 100% ethanol (slightly). |
存贮条件 | 储存温度2-8℃ |
描述
应用 | 强效钙通道蛋白抑制剂. |
产品介绍 | Nicardipine hydrochloride is the hydrochloride salt preparation of Nicardipine and a potent L-type calcium channel protein inhibitor. Nicardipine is described to alter cytochrome P-450 3A expression through induction of CYP3A. Nicardipine blockade of Ca2+ channels has been correlated to antihypertensive effects. |
备注 | Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders. |
别名 | 2,6-二甲基-4-(3-硝基苯基)-1,4-二氢-3,5-吡啶二羧酸-2-[甲基(苄基)氨基]乙基甲基酯盐酸盐;盐酸诺拉替坦;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride YC-93 |
标识符号 |
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信号词 | Danger |
危害声明 | H301-H311-H331 |
警示性声明 | P261-P280-P301 + P310-P311 |
个人防护设备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
RTECS | US7972100 |
WGK德国 | 3 |
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