G126481-50mgGSK2334470
面议
- 阿拉丁
- 生产商
- G126481-50mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C25H34N8O
- 分子量462.59
- MDL号 MFCD21608525
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
应用 | A potent and selective PDK1 inhibitor that subsequently induces apoptotic cell death |
产品介绍 | GSK2334470是PDK1抑制剂,IC50为10 nM,对别的相关AGC激酶无活性。 |
生化机理 | GSK2334470 is a highly specific and potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1). GSK2334470 can be used in cells to ablate T-loop phosphorylation and activate SGK, S6K1 and RSK as well as suppress the activation of Akt. |
别名 | GSK 2334470;GSK-2334470;GSK 2334470;GSK-2334470;(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide |
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