N159149-250mg1-萘羟肟酸
面议
- 阿拉丁
- 生产商
- N159149-250mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C11H9NO2
- 分子量187.20
- Beilstein号
- EC号
- MDL号 MFCD00059546
- PubChem编号
属性
溶解性 | DMSO: ≥5 mg/mL |
描述
生化机理 | 1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. 1-Naphthohydroxamic acid selectively inhibits HDAC8 (IC50 = 14 μM) over class I HDAC1 and class II HDAC6 (IC50 >100 μM). Treatment of cells with 1-Naphthohydroxamic acid does not increase neither global histone H4 nor tubulin acetylation . Also in contrast to the pan-HDAC inhibitors the compound is not reducing total intracellular HDAC activity. |
别名 | α-萘羟肟酸;N-Hydroxynaphthalene-1-carboxamide;a-Naphthohydroxamic acid |
Reaxys-RN | 2094470 |
RTECS | QJ1894500 |
WGK德国 | 3 |
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