Lansoprazole
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分子式 C16H14F3N3O2S 分子量369.36 Beilstein号 EC号 MDL号 MFCD00866873 PubChem编号 24278520 属性 熔点 173-175°C 溶解性 Soluble in methanol,
| 货号 | CAS号 | 操作 |
|---|---|---|
| L129650-1g | 103577-45-3 | 询底价 |
| L129650-100g | 103577-45-3 | 询底价 |
| L129650-250mg | 103577-45-3 | 询底价 |
| L129650-25g | 103577-45-3 | 询底价 |
| L129650-5g | 103577-45-3 | 询底价 |
耗材描述
- 分子式 C16H14F3N3O2S
- 分子量369.36
- Beilstein号
- EC号
- MDL号 MFCD00866873
- PubChem编号 24278520
属性
| 熔点 | 173-175°C |
| 溶解性 | Soluble in methanol, ethanol (14 mg/ml at 25 °C), DMF (~30 mg/ml), and DMSO (74 mg/ml at 25 °C). Insoluble in water. |
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | A H+,K+-ATPase inhibitor that displays antisecretory activity |
| 产品介绍 | Lansoprazole is a ATP4A (H+,K+-ATPase) inhibitor (IC50 = 6.3 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50 = 0.09 μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro. Also blocks swelling-dependent chloride channel (ICI swell) in NIH3T3 fibroblasts. Lansoprazole is more potent than omeprazole |
| 备注 | Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid. |
| 别名 | 兰索拉唑;南索拉唑;2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole |
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