耗材描述

• 分子式 C₂₀H₁₅ClN₄.2HCl
• 分子量419.74

属性

溶解性	DMSO 85 mg/mL Water 10 mg/mL Ethanol 6 mg/mL
存贮条件	储存温度-20°C

描述

备注	Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 1/2.
生化机理	Vatalanib (PTK787) is a novel VEGFR and c-Kit tyrosine kinases and angiogenesis inhibitor with IC50 of 0.037, 0.077, 0.27 and 0.73 μM for KDR, Flt-1, Flk and c-Kit, respectively.
别名	N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride;N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine dihydrochloride

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