E129590-50mgPF-3716556
面议
- 阿拉丁
- 生产商
- E129590-50mg
- 现货
- 全国
规格 |
---|
耗材描述
- 分子式 C22H26N4O3
- 分子量394.47
- MDL号 MFCD19690947
属性
溶解性 |
|
存贮条件 | 储存温度 2-8°C |
描述
应用 | A highly selective H+,K+-ATPase inhibitor that is more potent in acidic conditions. |
产品介绍 | PF-3716556是一种有效的,选择性的P-CAB钾离子竞争性酸抑制剂,在离子渗透和离子密集检测中,抑制猪H+,K+-ATPase活性,抑制胃酸分泌,对Na+,K+-ATPas没有作用活性,用于治疗胃食管返流疾病。 |
合法信息 | Sold for only research purposes |
备注 | PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, i |
生化机理 | PF 3716556 is a highly selective H+,K+-ATPase inhibitor which has been found to be more potent in acidic conditions. |
别名 | 8-[[(4R)-3,4-二氢-5-甲基-2H-1-苯并吡喃-4-基]氨基]-N-(2-羟基乙基)-N,2-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺;PF-03716556;PF03716556;8-[[(4R)-3,4-Dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethylimidazo[1,2-a]pyridine-6-carboxamide |
猜你喜欢
感兴趣产品