N,N'-Dimethylthiourea | N,N-二甲基硫脲 | MedChemExpress (MCE)
品牌 | 厂商性质 | 产地 | 货期 | 价格 |
---|---|---|---|---|
MedChemExpress (MCE) | 生产商 | 美国 | 现货 | 550 |
性能特点
N,N'-Dimethylthiourea (DMTU) 是从黑蒜中分离出来的,是口服有效的羟基自由基 (•OH) 的清除剂,通过活化的中性粒细胞在体外阻止 •OH 的产生。N,N'-Dime
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mM * 1 mL | 534-13-4 | ¥550.00 | 询底价 |
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N,N'-Dimethylthiourea
CAS No. : 534-13-4
MCE 国际站:N,N'-Dimethylthiourea
产品活性:N,N'-Dimethylthiourea (DMTU) 是从黑蒜中分离出来的,是口服有效的羟基自由基 (•OH) 的清除剂,通过活化的中性粒细胞在体外阻止 •OH 的产生。N,N'-Dimethylthiourea 通过发挥抗氧化作用,包括 •OH 清除和抗炎作用,防止水浸限制应激 (WIRS) 诱导的大鼠胃粘膜损伤。
研究领域:Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease
作用靶点:Reactive Oxygen Species
In Vivo: N,N'-Dimethylthiourea (DMTU; 1, 2.5, or 5 mmol/kg; orally) administered at 0.5 h before the onset of WIRS reduces the severity of gastric mucosal lesions with attenuation of the changes in the levels of gastric mucosal MPO, pro-inflammatory cytokines, LPO, NOx, nonprotein SH, and vitamin C and gastric adherent mucus found at 3 h after the onset of WIRS in a dose-dependent manner in Male Wistar rats aged 6 weeks.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途