PRDX3 抗体 (YA909) | MedChemExpress (MCE)

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PRDX3 Antibody (YA909)

MCE 国际站：PRDX3 Antibody (YA909)

PRDX3 Antibody (YA909) 是一个非偶联、分子量约 28 kDa、人源、抗 PRDX3 (YA909) 单克隆抗体。PRDX3 Antibody (YA909) 可用于：人背景下 WB, IF-Cell, IHC-P, FC, IP 实验，且不带标记。

Synonyms: PRDX3; AOP1; Thioredoxin-dependent peroxide reductase; mitochondrial; Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog

研究背景：Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

基因 ID：10935

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