Repaglinide | 瑞格列奈 | MedChemExpress (MCE)
品牌 | 厂商性质 | 产地 | 货期 | 价格 |
---|---|---|---|---|
MedChemExpress (MCE) | 生产商 | 美国 | 现货 | 785 |
性能特点
Repaglinide 是用于2 型糖尿病的胰岛素促分泌剂 (insulin secretagogue)。
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mM * 1 mL | 135062-02-1 | ¥785.00 | 询底价 |
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Repaglinide
CAS No. : 135062-02-1
MCE 国际站:Repaglinide
产品活性:Repaglinide 是用于2 型糖尿病的胰岛素促分泌剂 (insulin secretagogue)。
研究领域:Membrane Transporter/Ion Channel
作用靶点:Potassium Channel
In Vitro: Repaglinide reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted.
In Vivo: Repaglinide (AG-EE 623ZW) is very rapidly absorbed (tmax less than 1 hour) with a t1/2 of less than one hour. Furthermore, Repaglinide is inactivated in the liver and more than 90 % excreted via the bile. Repaglinide (1 mg/kg p.o.) is effective (P<0.001) as an insulin-releasing agent in a rat model (low-dose streptozotocin) of type 2 diabetes.
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