Chromium picolinate | MedChemExpress (MCE)

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Chromium picolinate

CAS No. : 14639-25-9

MCE 国际站：Chromium picolinate

产品活性：Chromium picolinate (Chromium (III) picolinate) 是一种具有口服活性的化合物。Chromium picolinate 可诱导细胞凋亡 (apoptosis)。Chromium picolinate 是 p38 MAPK 的激活剂。Chromium picolinate 有抗氧化活性。Chromium picolinate 可用于 2 型糖尿病的研究。

研究领域：Apoptosis  |  MAPK/ERK Pathway

作用靶点：Apoptosis  |  p38 MAPK

In Vitro: Chromium picolinate (5-100 μM, 24-72 h) induces lymphocyte apoptosis through ROS and mitochondrial events.
Chromium picolinate (100 nM, 24 h) exerts hypoglycemic effects in insulin-resistant 3T3-L1 adipocytes by activating p38 MAPK.

In Vivo: Chromium picolinate (100 mg/kg/day, orally, once daily for 4 weeks) causes weight gain and improves insulin sensitivity in Goto-Kakizaki diabetic rats.
Chromium picolinate (1 mg/kg/day, orally, once a daily for 4 weeks) can reduce the oxidative stress response of hyperglycemia induced by streptozotocin (HY-13753) in diabetic rats.

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