Angiotensin II 5-valine | 血管紧张素 Ⅱ 5-缬氨酸 | MedChemExpress (MCE)

Angiotensin II 5-valine 产品活性：Angiotensin II 5-valine 是血管紧张素受体 (angiotensin receptor) 的激动剂。 产品来源： https://www.medchemexpress.cn/Angiotensin-II-5-valine.html 研究领域：GPCR/G Protein 作用靶点：Angiotensin Receptor In Vivo: By day 12, systolic blood pressure (SBP) increases significantly in Angiotensin II 5-valine infused rats (197±7 mm Hg).The development of hypertension in ANG II infused rats is prevented by losartan treatment. Blood and kidney samples are harvested, subjected to HPLC to separate Angiotensin II 5-valine (exogenous) from Ile5-ANG II (endogenous) and the fractions are measured by radioimmunoassay. In the Angiotensin II 5-valine infused rats treated with losartan, total plasma ANG II levels are elevated to a greater extent than in rats not treated with losartan (289±20 v 119±14 fmol/mL). However, losartan markedly decrease by 88% the enhancement of intrarenal Val5-ANG II content that occurred in the rats infused with Val5-ANG II alone. 相关产品：Bioactive Compound Library Plus | Peptidomimetic Library | Peptide Library | Angiotensin II human | Losartan | Telmisartan | Tranilast | Valsartan | A 779 | Buloxibutid | AVE 0991 | Irbesartan | Candesartan | Nitrosoglutathione | YS-49 | Olmesartan | Olodanrigan | PD 123319 ditrifluoroacetate | Sparsentan | Alamandine | Azilsartan medoxomil | CGP-42112 | Talfirastide acetate | TRV-120027 | Angiotensin III, human, mouse 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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