Chelidonine | 白屈菜碱 | MedChemExpress (MCE)

Chelidonine 产品活性：Chelidonine 是一种异喹啉生物碱，可从白屈菜中提取出。Chelidonine 能导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡 (apoptosis)，也能阻止 Dugesia japonica 的干细胞细胞周期进程。Chelidonine 对黑色素细胞瘤具有细胞毒性活性。具有抗肿瘤和抗病毒活性。 产品来源： https://www.medchemexpress.cn/chelidonine.html 研究领域：Apoptosis | Anti-infection 作用靶点：Apoptosis | Influenza Virus 来源：植物 | 罂粟科 | 白屈菜 结构分类：生物碱 | 异喹啉类生物碱 | 结构分类 In Vitro: Chelidonine (5, 10 and 20 μM; 3-4 days) causes lesions and ventral curling in Dugesia japonica; and significantly decreases Djmcm2 expression at 20 μM but no reduction is observed at 5 and 10 μM; as well as prevents cell cycle progression of stem cells. Chelidonine (0-3 μg/mL; 48 h) has cytotoxic activity against melanoma cell lines. Chelidonine (1, 2 and 3 μg/mL; 24 h) decreases mitochondrial membrane potential (MMP) in 50% of A-375 cells at 1 and 1.5 μg/mL, and 62% at 3 μg/mL. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Apoptosis Compound Library | Natural Product Library | Anti-Cancer Compound Library | Antiviral Compound Library | CNS-Penetrant Compound Library | Traditional Chinese Medicine Active Compound Library | Alkaloids Library | Anti-Cancer Natural Product Library | Antiviral Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib | Monomethyl auristatin E | DAPT 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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