Methyl p-coumarate | 4-羟基肉桂酸甲酯 | MedChemExpress (MCE)

Methyl p-coumarate 产品活性：Methyl p-coumarate (Methyl 4-hydroxycinnamate)，一种可从 Trixis michuacana var longifolia 的花中分离出来的具有口服活性的对香豆酸 (pCA) 的酯化衍生物。Methyl p-coumarate 可抑制 B16 小鼠黑素瘤细胞中黑色素的形成。Methyl p-coumarate 对链格孢菌和其他病原体也具有很强的体外抑制作用。 产品来源： https://www.medchemexpress.cn/methyl-p-coumarate.html 研究领域：Anti-infection 作用靶点：Fungal 来源：植物 | 其他科 结构分类：苯丙素类 | 简单苯丙素 | 酚类 | 单酚类 | 结构分类 In Vitro: Methyl p-coumarate (10 μM) inhibits melanin formation in B16 mouse melanoma cells. Methyl p-coumarate (200 μg/mL) shows antifungal activity against A. alternata, and inhibits Alternaria rot in jujube fruit. Methyl p-coumarate (0-100 μM, 1 h) shows anti-inflammatory activity on Phorbol 12-myristate 13-acetate (HY-18739) (10 nM, 18 h)-stimulated A549 cells by suppressing the secretion of IL-6, IL-8, MCP-1, and ICAM-1. Methyl p-coumarate (0-100 μM, 1 h) inhibits activation of NF-κB/AP-1 in Phorbol 12-myristate 13-acetate (HY-18739) (10 nM, 18 h)-stimulated A549 cells. In Vivo: Methyl p-coumarate (5 mg/kg, p.o.) inhibits airway inflammation in Ovalbumins (HY-W250978)-induced mice with allergic asthma. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Natural Product Library | Anti-Cancer Compound Library | Fragment Library | Antifungal Compound Library | Medicine Food Homology Compound Library | Phenols Library | Orally Active Compound Library | Traditional Chinese Medicine Active Compound Library | Food-Sourced Compound Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Bioactive Compound Library Max | Rapamycin | Ferrostatin-1 | Cycloheximide | Staurosporine | Hygromycin B | Resveratrol | Tunicamycin | Oligomycin | Camptothecin | Filipin complex | Amphotericin B | Calcimycin | Monensin sodium | Nystatin | Ketoconazole | Itraconazole | Fluconazole | Valinomycin | Tofacitinib citrate | Caspofungin diacetate | Mycophenolic acid | Leptomycin B | Idarubicin hydrochloride | Toyocamycin | Terbinafine | Hyperoside | Saponins | Sinefungin | Carvacrol 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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