HG-14-10-04 | MedChemExpress (MCE)

HG-14-10-04 产品活性：HG-14-10-04 是一种有效的 ALK 和突变 EGFR 抑制剂，对 ALK、EGFRLR/TM、EGFR19del/TM/CS 和 EGFRLR/TM/CS 的 IC50 分别为 20 nM、15.6 nM、22.6 nM 和 124.5 nM。 产品来源： https://www.medchemexpress.cn/HG-14-10-04.html 研究领域：Protein Tyrosine Kinase/RTK | JAK/STAT Signaling 作用靶点：Anaplastic lymphoma kinase (ALK) | EGFR In Vitro: HG-14-10-04 (example 10) has inhibitory activity against ALK kinase with an IC50 of 20 nM. HG-14-10-04 (compound 17b) exhibits kinase inhibitory activity against EGFRLR/TM, EGFR19del/TM/CS and EGFRLR/TM/CS with IC50s of 15.6 nM, 22.6 nM and 124.5 nM, respectively. 相关产品：Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | JAK/STAT Compound Library | Kinase Inhibitor Library | Protein Tyrosine Kinase Compound Library | Anti-Cancer Compound Library | Differentiation Inducing Compound Library | Anti-Hepatitis C Virus Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Obesity Compound Library | Angiogenesis-Related Compound Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Prostate Cancer Compound Library | Cancer Stem Cells Compound Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Cytokine Inhibitors Library | Serine/Threonine Kinase Inhibitor Library | Anti-Ovarian Cancer Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Osimertinib | Trastuzumab | Gefitinib | Cetuximab | Erlotinib | Afatinib | Trastuzumab deruxtecan | Crizotinib | Lapatinib | AG490 | Genistein | Lorlatinib | Ceritinib | Neratinib | Trastuzumab emtansine | Tucatinib | Entrectinib | Alectinib | Brigatinib | Dacomitinib | AG-1478 | Pertuzumab | Disitamab vedotin | Mobocertinib | NSC 228155 | Repotrectinib | Amivantamab 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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