产品11
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Targetmol | 生产商 | 美国 | 现货 |
性能特点
性能1
货号 | 规格 | CAS号 | 价格 | 操作 |
---|---|---|---|---|
HH1231-222 | 1000m | 123-12-112 | ¥12,345.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Calcineurin A/PPP3CA Protein, Human, Recombinant (His)
描述: PPP3CA, also known as protein phosphatase 2B, is a member of the PPP phosphatase family, PP-2B subfamily. It is the alpha catalytic subunit of protein phosphatase 2B (PP2B). PP2B is a holoenzyme that is comprised of a catalytic subunit associated with regulatory subunits. It is a calcium regulated enzyme that is activated by calmodulin and participates in the signaling cascades involved in development of the nervous, cardiovascular, and musculoskeletal systems. PPP3CA activates the T cells of the immune system and can be blocked by drugs. It also activates NFATc (a transcription factor) by dephosphorylating it. The activated NFATc is subsequently translocated into the nucleus, where it upregulates the expression of interleukin 2. PPP3CA interacts with CRTC2, MYOZ1, MYOZ2 and MYOZ3. It also interacts with DNM1L. The interaction dephosphorylates DNM1L and regulates its translocation to mitochondria.
存储条件::: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: CNA 1 | CALNA 1 | CCN 1 | CALNA-1 | CCN-1 | CNA-1
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途