| Catalogue Number | ANT-132 |
| Synonyms | gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4, CD4mut. |
| Type | Mouse Anti Human Monoclonal. |
| Introduction | CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized. |
| Clone | hCD4. |
| Immunogen | Purified human PBL CD4+ T cells. |
| Ig Subclass | Mouse IgG2b. |
| Purification Method | Ion exchange column. |
| Protein concentration | 1mg/ml in PBS (after reconstitution). |
| Storage Procedures | Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |
| Reconstitution | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC. |
| Antibody Properties | Blocking and staining antibody. Blocks blinding of HIV to CD4. For staining, use 10 ml/106 cells. Titer for blocking T cell activation should be determined by the investigator. |
| Available Conjugates | This antibody is also available conjugated to biotin. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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