PF-04929113 (SNX-5422)-分析测试百科网

PF-04929113 (SNX-5422)

面议

分子式 C25H30F3N5O4 分子量521.54 属性溶解性 DMSO 104 mg/mL Water <1 mg/mL Ethanol 5 mg/mL 存贮条件储存温度-20°C //decorateTable('produ

400-6699-117 转1000

耗材描述

溶解性	DMSO 104 mg/mL Water <1 mg/mL Ethanol 5 mg/mL
存贮条件	储存温度-20°C

备注	PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with K_d of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.
生化机理	PF-04929113 is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.
别名	(1r,4r)-4-(2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)phenylamino)cyclohexyl 2-aminoacetate;(1r,4r)-4-(2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)phenylamino)cyclohexyl 2-aminoacetate