Levosimendan
面议
- 阿拉丁
- 生产商
- 国产
- 上海
- 现货
- 全国
- 5
- 0
分子式 C14H12N6O 分子量280.28 MDL号 MFCD00867135 属性 熔点 210-214 °C 溶解性 Soluble in water (<1 mg/ml), DMSO (56 mg/ml), methanol
| 货号 | CAS号 | 操作 |
|---|---|---|
| L129925-500mg | 141505-33-1 | 询底价 |
| L129925-1g | 141505-33-1 | 询底价 |
| L129925-50mg | 141505-33-1 | 询底价 |
| L129925-100mg | 141505-33-1 | 询底价 |
| L129925-250mg | 141505-33-1 | 询底价 |
耗材描述
- 分子式 C14H12N6O
- 分子量280.28
- MDL号 MFCD00867135
属性
| 熔点 | 210-214 °C |
| 溶解性 | Soluble in water (<1 mg/ml), DMSO (56 mg/ml), methanol, and ethanol (<1 mg/ml). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A Ca2+ sensitizer that increases contractile force of the myocardium. |
| 产品介绍 | Levosimendan 是一种钙增敏剂，通过与cardiac troponin C (cTnC)结合而发挥作用，这种作用具有钙依赖性。 |
| 备注 | Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure. Phase 4. |
| 生化机理 | Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration. Levosimendan has been shown to reduce circulating proinflammatory cytokine interleukin-6 and soluble apoptosis mediators. Levosimendan is an inhibitor of PDE. |
| 别名 | 左西孟旦; 左旋西孟旦;OR1259; (-)-OR-1259; (R)-Simendan; 2-[2-[4-[(4R)-1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazinylidene]-propanedinitrile; OR 1259; (R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile;Simdax; Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6- oxo-3-pyridazinyl)phenyl)hydrazone |
猜你喜欢
感兴趣产品