蛎灰菌素A
面议
- 阿拉丁
- 生产商
- 国产
- 上海
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分子式 C28H35N3O7 分子量525.59 EC号 244-376-6 MDL号 MFCD00869411 PubChem编号 24900736 属性 溶解性 Soluble in water (partly), ethanol (4
货号 | CAS号 | 操作 |
---|---|---|
V102390-5mg | 21411-53-0 | 询底价 |
耗材描述
- 分子式 C28H35N3O7
- 分子量525.59
- EC号 244-376-6
- MDL号 MFCD00869411
- PubChem编号 24900736
属性
溶解性 | Soluble in water (partly), ethanol (4%), methanol (4%), DMF, and DMSO. |
存贮条件 | 储存温度-20°C |
密度 | 1.2600 |
描述
应用 | A bacteriostatic inhibitor of translation at the 50S ribosome |
产品介绍 | Ostreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria. |
生化机理 | Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo |
别名 | 春霉素 A;Mikamycin A;Staphylomycin |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 3 |
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