D-青霉胺
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分子式 C5H11NO2S 分子量149.21 Beilstein号 1722375 EC号 200-148-8 MDL号 MFCD00064302 PubChem编号 24898564 属性 沸点 251.8° C 熔点 210° C 折
| 货号 | CAS号 | 操作 |
|---|---|---|
| P115952-100g | 52-67-5 | 询底价 |
| P115952-25g | 52-67-5 | 询底价 |
| P115952-5g | 52-67-5 | 询底价 |
耗材描述
- 分子式 C5H11NO2S
- 分子量149.21
- Beilstein号 1722375
- EC号 200-148-8
- MDL号 MFCD00064302
- PubChem编号 24898564
属性
| 沸点 | 251.8° C |
| 熔点 | 210° C |
| 折光率 | 1.53 |
| 旋光率 | -63o |
| 溶解性 | Soluble in water (30 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), methanol, and DMSO (<1 mg/ml at 25° C) |
| 存贮条件 | 储存温度2-8℃ |
| 密度 | 1.2000 |
描述
| 应用 | It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes. |
| 产品介绍 | Penicillamine is an exogenous NOS modulator, found to inhibit urease activity. |
| 生化机理 | Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity. |
| 别名 | 3,3-二甲基-D-半胱氨酸; 3-巯基-D-缬氨酸; D-(-)-2-氨基-3-巯基-3-甲基丁酸; 二甲基半胱胺酸; β-巯基缬氨酸; D-(-)-青霉胺;Cuprimine; 3-Mercapto-D-valine; Mercaptovaline; Penicillamine; D-β,β-Dimethylcysteine; D-(?)-2-Amino-3-mercapto-3-methylbutanoic acid; D-β-Mercaptovaline;3,3-Dimethyl-D-cysteine |
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