耗材描述

• 分子式 C₅₀H₇₁N₁₃O₁₂
• 分子量1046.18
• Beilstein号
• EC号
• MDL号
• PubChem编号 24891466

属性

敏感性	热敏感
溶解性	Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
存贮条件	-20℃保存
密度	1.4300

描述

应用	A peptide involved in the regulation of blood pressure
产品介绍	Angiotensin II plays an important role in the regulation of blood pressure and has strong vasoconstrictive effects. It also stimulates the release of aldosterone from the adrenal gland and inhibits adenylate cyclase activity in spontaneously hypertensive rats. Angiotensin II increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase (MYLK). It also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons and activates JAK2 in smooth muscle cells. Furthermore, angiotensin II activates FAK (p125FAK) and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. It also activates c-Src (p60c-src), ERK1/2, JNK, and p38α (p38 MAP Kinase) in vascular smooth muscle cells. The amino acid sequence Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
别名	;Hypertensin II; Ang II; DRVYIHPF;

个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS	BW2165000
WGK德国	3

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