耗材描述

• 分子式 C₁₇H₁₄N₂
• 分子量246.31
• MDL号 MFCD00195766

属性

熔点	165.0-171.0°C
存贮条件	储存温度 2-8°C

描述

应用	An antineoplastic agent that activates Chk 2 and cytochrome p450
产品介绍	3,3'-Diindolylmethane is an anticancer and antineoplastic agent. 3,3'-Diindolylmethane induces apoptosis in human cancer cells. 3,3'-Diindolylmethane is also an activator of CYP (cytochrome P450) and Chk2 (checkpoint kinase 2) as well as a partial agonist of aryl hydrocarbon receptor (Ah Receptor). The compound is a dimer of indole-3-carbinol.
生化机理	Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol.It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells.DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor.The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.
别名	二(3,3'-吲哚基)甲烷;3,3'-二吲哚甲烷;DIM;Di-3-indolylmethane; Plant Indole; 3,3’-Methylenediindole;DIM

标识符号	GHS07
信号词	Warning
危害声明	H315,H319,H335,H413
警示性声明	P261,P305+P351+P338
个人防护设备	dust mask type N95 (US), Eyeshields, Gloves
WGK德国	3
风险声明 (欧洲)	R36/37/38
安全声明（欧洲）	S26
危害码（欧洲）	Xi

猜你喜欢

• 

  2-甲基吲哚-3-甲醛

• 

  1-亚硝基吡咯烷

• 

  6-氨基吡啶-2-羧酸

• 

  10-羟基苯并[ h] 喹啉

• 

  5-溴-2-甲氧基嘧啶

• 

  4-(N,N-二甲氨基磺酰基)-7-氨基-2,1,3-苯并恶二唑

• 

  1-甲基吡唑-4-甲酸

• 

  2,5-二(2-噻吩)-1H-吡咯

• 

  4-氯-6,7-二甲氧基喹唑啉

• 

  苯并咪唑

感兴趣产品

• 3,3'-亚甲基二吲哚价格
• 3,3'-亚甲基二吲哚厂商
• 3,3'-亚甲基二吲哚规格