化合物CDDO-2P-Im T13602
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Product IntroductionBioactivity英文名: CDDO-2P-Im描述: CDDO-2P-Im 在小鼠肺癌模型中显示出化学预防作用并降低了肺肿瘤的大小和严重程度。体外活性: 在RAW264.7细胞中，CDDO-2P-
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Product Introduction
Bioactivity
英文名: CDDO-2P-Im
描述: CDDO-2P-Im 在小鼠肺癌模型中显示出化学预防作用并降低了肺肿瘤的大小和严重程度。
体外活性: 在RAW264.7细胞中，CDDO-2P-Im可以抑制NO的生成（IC50：5.8 nM）。CDDO-2P-Im（100 nM）能诱导U937细胞分化[1]。
体内活性: CDDO-2P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels. In A/J mice, CDDO-2P-Im (50-200 mg/kg) decreases the number, size, and severity of tumors[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 112.5 mg/mL (181.8 mM)
关键字: CDDO-2P-Im
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Lung Cancer Compound Library | Anti-Cancer Active Compound Library | Covalent Inhibitor Library | Bioactive Compound Library
Bioactivity
英文名: CDDO-2P-Im
描述: CDDO-2P-Im 在小鼠肺癌模型中显示出化学预防作用并降低了肺肿瘤的大小和严重程度。
体外活性: 在RAW264.7细胞中，CDDO-2P-Im可以抑制NO的生成（IC50：5.8 nM）。CDDO-2P-Im（100 nM）能诱导U937细胞分化[1]。
体内活性: CDDO-2P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels. In A/J mice, CDDO-2P-Im (50-200 mg/kg) decreases the number, size, and severity of tumors[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 112.5 mg/mL (181.8 mM)
关键字: CDDO-2P-Im
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Lung Cancer Compound Library | Anti-Cancer Active Compound Library | Covalent Inhibitor Library | Bioactive Compound Library
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