Product IntroductionBioactivity英文名:
ML-9 Free Base描述: ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
体外活性: ML9 (free base) (50?μM; 1-4?hours) obviously enhances cleaved caspase-3 levels, decreased STIM1 protein levels by about 42%. ML9 (free base) (0-100?μM; 0-24?hours) has no reduction in cardiomyocyte viability, 50-100?μM obviously causes cell death [2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字:
ML 9 |
ML9 Free Base |
ML-9 Free Base |
ML 9 Free Base |
ML-9 |
ML9