化合物 T16103 T16103
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 110448-31-2 | ¥10,600.00 | 询底价 |
100 mg | 110448-31-2 | ¥17,500.00 | 询底价 |
50 mg | 110448-31-2 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: ML-9 Free Base
描述: ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
体外活性: ML9 (free base) (50?μM; 1-4?hours) obviously enhances cleaved caspase-3 levels, decreased STIM1 protein levels by about 42%. ML9 (free base) (0-100?μM; 0-24?hours) has no reduction in cardiomyocyte viability, 50-100?μM obviously causes cell death [2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: ML 9 | ML9 Free Base | ML-9 Free Base | ML 9 Free Base | ML-9 | ML9
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途